03-0183-00
SMC® Human UCHL1 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human UCHL1 in human serum, plasma, and cerebrospinal fluid (CSF)
Synonym(s):
Ubiquitin Carboxyl Terminal Hydrolase L1 immunoassay kit, NDGOA immunoassay kit, PARK5 immunoassay kit, PGP9.5 immunoassay kit, SPG79A immunoassay kit, UCH-L1 Single Molecule Counting kit, UCH-L1 ultra-sensitive immunoassay, Ubiquitin Carboxyl Terminal Hydrolase L1 Single Molecule Counting kit
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About This Item
Product Name
SMC® Human UCHL1 High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Human UCHL1 in human serum, plasma, and cerebrospinal fluid (CSF)
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
manufacturer/tradename
SMC®
technique(s)
single molecule counting: suitable
input
plasma (K2 EDTA)
cerebrospinal fluid (CSF)
serum
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
Legal Information
Analysis Note
- Sensitivity: LLOQ 2,600 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 1300-2,000,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 111% Plasma: 100% CSF: 96%
- Recovery: Serum: 92% Plasma: 93% CSF: 92%
Application
Biochem/physiol Actions
Disclaimer
Features and Benefits
- Ultrasensitive Measurement: Enables femtogram-level quantification of UCHL1 in serum, plasma, or CSF.
- Expanded Analytical Range: Improves signal clarity and minimizes background noise, ensuring consistent performance.
- Streamlined Assay Design: Follows a standard sandwich immunoassay format while delivering enhanced sensitivity for UCHL1 detection.
- Automation Compatible: Designed for integration with automated liquid handling platforms to reduce manual input and accelerate lab workflows.
- Dedicated Scientific Support: Supported by experienced field scientists and technical specialists.
General description
Abnormalities in UCHL1 expression or function can lead to the accumulation of misfolded or damaged proteins, contributing to neuronal stress and cell death. Additionally, UCHL1 is associated with neuroinflammation, as its dysregulation can exacerbate inflammatory responses in the brain. Understanding UCHL1′s role in these processes is crucial for developing therapeutic strategies aimed at enhancing protein degradation pathways and mitigating the effects of neurodegeneration and inflammation in neurological disorders.
Packaging
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Regulatory Information
Certificates of Analysis (COA)
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