Quality Level
usage
kit sufficient for 96 wells
quality
200
species reactivity
human
manufacturer/tradename
SMC®
assay range
linearity: 113%
(Serum)
linearity: 115%
(Plasma)
recovery range: 116%
(Serum)
recovery range: 98%
(Plasma)
sensitivity: 1.95-7.81 pg/mL
(Refer to CoA for lot-specific LLOQ)
standard curve range: 0.98-1,000 pg/mL
technique(s)
single molecule counting: suitable
input
plasma (K2EDTA)
serum
shipped in
wet ice
storage temp.
2-8°C
General description
IL-22 binding protein (IL-22BP) is a soluble protein that regulates the immune response by binding to IL-22 and preventing it from interacting with its receptor on target cells. This action serves as a negative regulator, helping maintain a balanced immune response and preventing excessive inflammation. IL-22BP may have therapeutic potential in treating autoimmune and inflammatory diseases by modulating IL-22 signaling.
Application
For ultrasensitive detection of IL-22BP in human serum and plasma
Features and Benefits
Features
- Robustness and Reproducibility: Lot-matched components ensure consistent assay performance across experiments, reducing variability and enhancing data reliability.
- Enhanced Detection Limits: Capable of detecting ultra-low analyte levels in the picogram and femtogram range, enabling the study of low-abundance biomarkers critical in early-stage research.
- Simplified Workflow Compatibility: Designed to align with standard assay workflows, including ELISA, minimizing the need for additional training or protocol adjustments.
- Certified Data Assurance: Each kit includes a Certificate of Analysis detailing validated assay characteristics, ensuring traceability and quality control for regulatory compliance.
- Wide Dynamic Range: Accurately quantifies analyte concentrations across a broad range, supporting both high and low abundance detection in complex samples.
- Automation Ready: Compatible with high-throughput systems, enabling seamless integration into automated workflows, reducing manual handling errors, and increasing efficiency.
- Understanding Mechanisms: By accurately measuring IL-22BP levels, you can explore its role in immune responses and pathophysiology, enhancing your understanding of disease mechanisms.
- Monitoring Disease Models: This ultrasensitive assay facilitates tracking of IL-22BP levels over time in your samples, helping you gain insights for research into disease progression and treatment effects.
- Early Detection: With enhanced sensitivity, this assay allows you to detect low concentrations of IL-22BP, enabling early identification of inflammatory and autoimmune conditions in your studies.
- Integrated Analysis: Having both IL-22BP and IL-22 assays on the same platform allows for streamlined data collection and analysis, enabling you to correlate IL-22 levels with its binding protein in a single workflow.
Legal Information
SMC is a registered trademark of Singulex
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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