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质量水平

用途

 kit sufficient for 96 wells

质量

200

种属反应性

human

制造商/商品名称

SMC®

assay range

linearity: 113%
(Serum)

linearity: 115%
(Plasma)

recovery range: 116%
(Serum)

recovery range: 98%
(Plasma)

sensitivity: 1.95-7.81 pg/mL
(Refer to CoA for lot-specific LLOQ)

standard curve range: 0.98-1,000 pg/mL

技术

single molecule counting: suitable

输入

plasma (K2EDTA)
serum

运输

wet ice

储存温度

2-8°C

一般描述

IL-22 binding protein (IL-22BP) is a soluble protein that regulates the immune response by binding to IL-22 and preventing it from interacting with its receptor on target cells. This action serves as a negative regulator, helping maintain a balanced immune response and preventing excessive inflammation. IL-22BP may have therapeutic potential in treating autoimmune and inflammatory diseases by modulating IL-22 signaling.

应用

For ultrasensitive detection of IL-22BP in human serum and plasma

特点和优势

Features
  • Robustness and Reproducibility: Lot-matched components ensure consistent assay performance across experiments, reducing variability and enhancing data reliability.
  • Enhanced Detection Limits: Capable of detecting ultra-low analyte levels in the picogram and femtogram range, enabling the study of low-abundance biomarkers critical in early-stage research.
  • Simplified Workflow Compatibility: Designed to align with standard assay workflows, including ELISA, minimizing the need for additional training or protocol adjustments.
  • Certified Data Assurance: Each kit includes a Certificate of Analysis detailing validated assay characteristics, ensuring traceability and quality control for regulatory compliance.
  • Wide Dynamic Range: Accurately quantifies analyte concentrations across a broad range, supporting both high and low abundance detection in complex samples.
  • Automation Ready: Compatible with high-throughput systems, enabling seamless integration into automated workflows, reducing manual handling errors, and increasing efficiency.
Benefits
  • Understanding Mechanisms: By accurately measuring IL-22BP levels, you can explore its role in immune responses and pathophysiology, enhancing your understanding of disease mechanisms.
  • Monitoring Disease Models: This ultrasensitive assay facilitates tracking of IL-22BP levels over time in your samples, helping you gain insights for research into disease progression and treatment effects.
  • Early Detection: With enhanced sensitivity, this assay allows you to detect low concentrations of IL-22BP, enabling early identification of inflammatory and autoimmune conditions in your studies.
  • Integrated Analysis: Having both IL-22BP and IL-22 assays on the same platform allows for streamlined data collection and analysis, enabling you to correlate IL-22 levels with its binding protein in a single workflow.

法律信息

SMC is a registered trademark of Singulex

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