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Merck
CN

05-1416

Anti-CD45 Antibody, clone IBL-5/25

clone IBL-5/25, from rat

Synonym(s):

CD45 associated protein, CD45-associated protein, Lymphocyte phosphatase-associated phosphoprotein, PTPRC-associated protein, protein tyrosine phosphatase, receptor type, C-associated protein, protein tyrosine phosphatase, receptor type, c

polyp

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-CD45 Antibody, clone IBL-5/25, clone IBL-5/25, from rat

biological source

rat

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

IBL-5/25, monoclonal

species reactivity

mouse

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable

isotype

IgG

NCBI accession no.

NP_002829.2

UniProt accession no.

Q14761

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

mouse ... Ptprc(19264)

Related Categories

Analysis Note

Control
Mouse colon tissue
Evaluated by Immunohistochemistry in mouse colon tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.

Application

Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.
Flow Cytometry Analysis: A previous lot detected CD45, clone IBL-5/25 in mouse peripheral blood lymphocytes

Biochem/physiol Actions

Reactivity with other species has not been determined.
This antibody reacts with all isoforms of mouse CD45 which is expressed on all haematopoietic cells except erythrocytes.
FUSION PARTNER: SP2/0 myeloma cell line

General description

CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.
Approx. 147 kDa

Immunogen

Mouse lymph node cells.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: CBL1326

Physical form

Format: Purified
Purified rat monoclonal IgG in phosphate buffered saline containing 10 mM sodium azide.

Preparation Note

Store at 2-8°C for 12 months from date of receipt.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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