05-643
Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3
clone 2D3, Upstate®, from mouse
Synonym(s):
Anti-7330414F15Rik, Anti-8430431H08Rik, Anti-C86142, Anti-GSK-3, Anti-GSK-3beta, Anti-GSK3
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
2D3, monoclonal
Species reactivity:
human, mouse, rat
Application:
electrophoretic mobility shift assay
western blot
western blot
Technique(s):
electrophoretic mobility shift assay: suitable
western blot: suitable
western blot: suitable
Citations:
14
Uniprot accession no.:
Product Name
Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3, clone 2D3, Upstate®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
2D3, monoclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
electrophoretic mobility shift assay: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer9)
Quality Level
Gene Information
human ... GSK3B(2932)
Physical form
Format: Purified
100µg of thiophilic and size exclusion chromatography purified mouse IgG1κ in 100µL of antibody storage buffer (PBS with PEG, Sucrose, and 0.09% sodium azide) and 50% glycerol.
Thiophilic adsorption chromatography
Analysis Note
routinely evaluated by immunoblot on L6 cells stimulated with IGF-1
Application
Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3 is an antibody against phospho-GSK3β (Ser9) for use in EMSA & WB.
Research Category
Signaling
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling
PI3K, Akt, & mTOR Signaling
Biochem/physiol Actions
GSK3beta
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
46kDa (GSK3β) and 51kDa (GSK3α)
Immunogen
peptide corresponding to amino acids 6-12 (RTT[pS]AE) of human GSK3beta
Other Notes
Replaces: 04-1075
Preparation Note
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Pei-Wen Cheng et al.
Biomedicines, 9(11) (2021-11-28)
Traumatic brain injury confers a significant and growing public health burden. It is a major environmental risk factor for dementia. Nonetheless, the mechanism by which primary mechanical injury leads to neurodegeneration and an increased risk of dementia-related diseases is unclear.
Hui Sheng et al.
International journal of medical sciences, 10(6), 782-789 (2013-05-01)
We previously reported that the constitutional flavonoid glycosides derived from herb Epimedium (EF, composed of seven flavonoid compounds with common nuclear stem) exerted beneficial effects on the bone, including promoting bone formation and inhibiting bone marrow fat deposition. Recent in
Tzyy-Yue Wong et al.
Journal of clinical medicine, 7(11) (2018-11-08)
The dynamics of a living body enables organs to experience mechanical stimulation at cellular level. The human cardiomyocytes cell line provides a source for simulating heart dynamics; however, a limited understanding of the mechanical stimulation effect on them has restricted
Yu-Te Lin et al.
Journal of clinical medicine, 7(10) (2018-10-12)
Recent studies have indicated that several anti-hypertensive drugs may delay the development and progression of Alzheimer's disease (AD). However, the relationships among AD, hypertension, and oxidative stress remain to be elucidated. Here, we aimed to determine whether reactive oxygen species
Laia Lidón et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Tau protein is largely responsible for tauopathies, including Alzheimer's disease (AD), where it accumulates in the brain as insoluble aggregates. Tau mRNA is regulated by alternative splicing, and inclusion or exclusion of exon 10 gives rise to the 3R and
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