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Merck
CN

05-652

Anti-MUC1/episialin Antibody, clone 214D4

clone 214D4, Upstate®, from mouse

Synonym(s):

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, Episialin, H23AG, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-MUC1/episialin Antibody, clone 214D4, clone 214D4, Upstate®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

clone

214D4, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable

isotype

IgG1

NCBI accession no.

NM_182741

UniProt accession no.

P15941

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Analysis Note

routinely evaluated by immunohistochemistry

Application

Anti-MUC1/episialin Antibody, clone 214D4 detects level of MUC1/episialin & has been published & validated for use in FC, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Biochem/physiol Actions

MUC1/episialin

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

none given

Immunogen

Fusion protein, human b-gal-episialin/MUC1 repeat domain

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

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Neeraja Dharmaraj et al.
Biology of reproduction, 81(6), 1182-1188 (2009-08-18)
Embryo implantation involves direct interaction of the blastocyst with the luminal epithelium of the receptive uterus. MUC1, a transmembrane mucin expressed at the apical surface of uterine epithelia, acts as a barrier to microbial infection and enzymatic attack. Loss of
Kelly A Correll et al.
Biochemical and biophysical research communications, 499(4), 843-848 (2018-04-06)
TGF beta is a multifunctional cytokine that regulates alveolar epithelial cells as well as immune cells and fibroblasts. TGF beta inhibits surfactant protein A, B and C expression in fetal human lung and can inhibit type II cell proliferation induced
Ilene K Gipson et al.
Cornea, 30(12), 1346-1352 (2011-11-18)
To determine if levels of the glycocalyx membrane mucins, MUC1 and MUC16, and the secreted goblet cell mucin MUC5AC are altered in conjunctival cells and tears of postmenopausal women presenting with a history of non-Sjögren dry eye and if mucin
Linjie Xiong et al.
Investigative ophthalmology & visual science, 52(8), 5641-5646 (2011-04-22)
Notch proteins are a family of transmembrane receptors that coordinate binary cell fate decisions and differentiation in wet-surfaced epithelia. We sought to determine whether Notch signaling contributes to maintaining mucosal homeostasis by modulating the biosynthesis of cell surface-associated mucins in
Ilene K Gipson et al.
Biology of reproduction, 78(1), 134-142 (2007-10-19)
In order for the preimplantation embryo to implant into the uterus, the trophoblast cells must initially adhere to the uterine epithelial surface. In preparation, the luminal secretory cells of the epithelium lose their nonadhesive character and their surface microvilli and
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