Skip to Content
Merck
CN

05-916

Anti-P-Cadherin Antibody, clone 6A9

ascites fluid, clone 6A9, Upstate®

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.43
eCl@ss:
32160702

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Anti-P-Cadherin Antibody, clone 6A9, ascites fluid, clone 6A9, Upstate®

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

6A9, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_001793

UniProt accession no.

P22223

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CDH3(1001)

Analysis Note

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Routinely evaluated by immunoblot on A431 cell lysates.

Application

This Anti-P-Cadherin Antibody, clone 6A9 is validated for use in IP, WB, IC for the detection of P-Cadherin.

Biochem/physiol Actions

Recognizes P-Cadherin

General description

Mr 120kDa

Immunogen

P-Cadherin extracellular domain purified from A431 cell membranes.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Differential displacement of classical cadherins by VE-cadherin
Jaggi, M., et al
Cell communication & adhesion, 9, 103-115 (2002)
M D Hines et al.
Journal of cell science, 112 ( Pt 24), 4569-4579 (1999-11-27)
Cadherin function is required for normal keratinocyte intercellular adhesion and stratification. In the present study, we have investigated whether cadherin-cadherin interactions may also modulate keratinocyte differentiation, as evidenced by alterations in the levels of several differentiation markers. Confluent keratinocyte cultures
Cadherin function is required for human keratinocytes to assemble desmosomes and stratify in response to calcium
Lewis, J. E., et al
The Journal of Investigative Dermatology, 102, 870-877 (1994)
K A Knudsen et al.
Human pathology, 31(8), 961-965 (2000-09-15)
Breast cancers often show reduced expression of the transmembrane cell-cell adhesion protein, E-cadherin. In addition, approximately half of breast carcinomas express P-cadherin, which correlates with poor survival. A large fragment of the E-cadherin extracellular domain can be detected in serum
M T Nieman et al.
Journal of cell science, 112 ( Pt 10), 1621-1632 (1999-04-23)
The cadherin/catenin complex mediates Ca2+-dependent cell-cell interactions that are essential for normal developmental processes. It has been proposed that sorting of cells during embryonic development is due, at least in part, to expression of different cadherin family members or to
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service