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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Pdx1(18609)
General description
Transcription factor PDX1, also known as pancreatic and duodenal homeobox 1, activates expression of the insulin and somatostatin genes. This protein is a key regulator of islet peptide hormone expression and also plays an essential role in pancreatic development. It has been shown to interact with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). This protein also interacts with the methyltransferase SETD7. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.
Immunogen
Recombinant protein corresponding to the N-terminus of mouse PDX1.
Application
Anti-PDX1 (goat) Antibody is a Goat Polyclonal Antibody for detection of PDX1 also known as pancreatic & duodenal homeobox 1, somatostatin transcription factor 1, Insulin promoter factor 1 & has been validated in WB & IHC.
Immunohistochemistry Analysis: 1:400 dilution from a represenative lot detected PDX1 in normal human pancreas tissue.
Quality
Evaluated by Western Blot in mouse pancreatic β T-cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected PDX1 on 10 µg of mouse pancreatic β T-cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected PDX1 on 10 µg of mouse pancreatic β T-cell lysate.
Target description
~ 39 kDa
Physical form
Unpurified goat polyclonal serum containing 0.05% sodium azide.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
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