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Sigma-Aldrich

Anti-PP2A Antibody, C subunit

serum, Upstate®

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eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human, rabbit, rat

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_002715.2
NP_002706

UniProt accession no.

P62714
P67775

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PPP2CA(5515)

Specificity

Recognizes PP2A-subunit alpha and PP2A-subunit beta; does not react with PP1 or other protein phosphatases.

Immunogen

peptide corresponding to the C-terminal amino acid residues 296-309 of human protein phosphatase 2A

Application

Anti-PP2A Antibody, C subunit is an antibody against PP2A for use in IP & WB.
Research Category
Signaling

Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neurodegenerative Diseases

Quality

routinely evaluated by immunoblot on a rabbit brain cytosol or in a human A431 RIPA cell lysate

Target description

36 kDa

Physical form

Immunoaffinity Purified immunoglobulin in 150mM Tris, pH 7.4, 0.02% sodium azide, 50% glycerol and 5mg/ml BSA
Unpurified

Storage and Stability

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Positive Control Included: Non-Stim A431 Cell Lysate (12-301). Other controls: HeLa whole cel lysate, mouse NIH3T3 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's disease.
Lee, KW; Im, JY; Woo, JM; Grosso, H; Kim, YS; Cristovao, AC; Sonsalla, PK; Schuster et al.
Neurotherapeutics null
Postnatal changes in contractile time parameters, calcium regulatory proteins, and phosphatases
Gombosova, I, et al.
The American Journal of Physiology, 274, H2123-H2132 (1998)
Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.
John D Imig,Christiana Dimitropoulou,D Sudarshan Reddy,Richard E White,John R Falck
Microcirculation (New York, N.Y. : 1994) (1994)
M Le Romancer et al.
The Journal of biological chemistry, 269(26), 17464-17468 (1994-07-01)
We previously reported the immunopurification of a somatostatin receptor from the human tumoral gastric cell HGT1 using the monoclonal antibody 30F3 (Reyl-Desmars, F., Le Roux, S., Linard, C., Benkouka, F., and Lewin, M. J. M. (1989) J. Biol. Chem. 264
CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression
Bito, H., et al
Cell, 87, 1203-1214 (1996)
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