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Merck
CN

06-554

Anti-STAT5B Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-STAT5B Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_012448

UniProt accession no.

P51692

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... STAT5B(6777)

Analysis Note

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on mouse 3T3/A31 or human A431 cell lysates

Application

Anti-STAT5B Antibody is a Rabbit Polyclonal Antibody for detection of STAT5B also known as signal transducer & activator of transcription 5B & has been tested in WB.

General description

90-92kDa

Immunogen

amino acids 774-787 of human STAT5B (CGRPMDSQWIPHAQS)

Physical form

Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Possible involvement of truncated signal transducer and activator of transcription-5 in the GH pattern-dependent regulation of CYP2C12 gene expression in rat liver.
Hanna Helander, Jan-Ake Gustafsson, Agneta Mode
Molecular Endocrinology null
J X Lin et al.
The Journal of biological chemistry, 271(18), 10738-10744 (1996-05-03)
We have isolated a second human Stat5 cDNA, Stat5B, and demonstrated that the genes encoding both Stat5A and Stat5B are located at chromosome 17q11.2. Both genes were constitutively transcribed in peripheral blood lymphocytes. By using specific antisera, we demonstrated that
Src Kinases Mediate STAT Growth Pathways in Squamous Cell Carcinoma of the Head and Neck
Xi, S., et al
The Journal of Biological Chemistry, 278, 31574-31583 (2003)
B Millot et al.
The Biochemical journal, 359(Pt 3), 557-565 (2001-10-24)
The aim of the present study was to identify the functional domains of the upstream region of the rabbit whey acidic protein (WAP) gene, which has been used with considerable efficacy to target the expression of several foreign genes to
Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.
Ghosh, P; Buchholz, MA; Yano, S; Taub, D; Longo, DL
Blood null
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JAK/STAT Signaling Research Focus

The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a variety of cytokines and growth factors. Constitutive activation or dysregulation of JAK/STAT signaling can result in inflammatory disease, erythrocytosis, gigantism, and leukemia.

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