07-436-AF488
Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor™ 488 Conjugate
0.5 mg/mL, from rabbit
Synonym(s):
Histone H3.1t, H3/t, H3t, H3/g
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR™ 488
Clone:
polyclonal
Application:
ICC
Citations:
-
biological source
rabbit
Quality Segment
conjugate
ALEXA FLUOR™ 488
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
species reactivity (predicted by homology)
vertebrates (based on 100% sequence homology)
concentration
0.5 mg/mL
technique(s)
immunocytochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
monomethylation (Lys4)
Gene Information
human ... H3C1(8350)
General description
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-436.
~17 kDa observed (Refer to Cat. No. 07-436)
Immunogen
Linear peptide corresponding to Histone H3 monomethylated at Lys4.
Application
This Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor™ 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).
Physical form
Purified rabbit Alexa Fluor™ 488 conjugated antibody in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.
Analysis Note
Evaluated by Immunocytochemisty Analysis in HeLa cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.
Alexa Fluor™ is a registered trademark of Life Technologies
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.
Alexa Fluor™ is a registered trademark of Life Technologies
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
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