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Merck
CN

07-471

Anti-Daxx Antibody

serum, Upstate®

Synonym(s):

Anti-BING2, Anti-DAP6, Anti-EAP1, Anti-SMIM40

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunocytochemistry
immunoprecipitation (IP)
western blot
Species reactivity:
human, rat, mouse, hamster
Citations:
36
Technique(s):
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
Q9UER7

Key Documents

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Product Name

Anti-Daxx Antibody, serum, Upstate®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse, hamster

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_001350

UniProt accession no.

Q9UER7

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

hamster ... Daxx(101836409)
human ... DAXX(1616)
mouse ... Daxx(13163)
rat ... Daxx(140926)

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
routinely evaluated by immunoblot in HeLa nuclear extract

Application

Anti-Daxx Antibody is an antibody against Daxx for use in IP, WB & IC.

Biochem/physiol Actions

Daxx

General description

110 kDa

Immunogen

GST fusion protein corresponding to residues 472-740 of human Daxx.

Other Notes

Replaces: 04-445

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sarah Müncheberg et al.
Journal of virology, 92(13) (2018-04-27)
Human adenovirus (HAdV) E1B-55K is a multifunctional regulator of productive viral replication and oncogenic transformation in nonpermissive mammalian cells. These functions depend on E1B-55K's posttranslational modification with the SUMO protein and its binding to HAdV E4orf6. Both early viral proteins
PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication.
Cuchet, D; Sykes, A; Nicolas, A; Orr, A; Murray, J; Sirma, H; Heeren, J; Bartelt, A; Everett, RD
Journal of Cell Science null
Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins.
RD Everett, C Boutell, C McNair, L Grant, A Orr
Journal of virology null
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.
Cuchet-Lourenco, D; Boutell, C; Lukashchuk, V; Grant, K; Sykes, A; Murray, J; Orr, A; Everett, RD
PLoS Pathogens null
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.
Schreiner, S; Burck, C; Glass, M; Groitl, P; Wimmer, P; Kinkley, S; Mund, A; Everett, RD; Dobner, T
Nucleic Acids Research null
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