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Merck
CN

07-594

Sigma-Aldrich

Anti-Histone H2A.Z Antibody

serum, Upstate®

Synonym(s):

Anti-H2A.Z-1, Anti-H2A.z, Anti-H2A/z, Anti-H2AFZ, Anti-H2AZ

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

packaging

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

UniProt accession no.

shipped in

ambient

target post-translational modification

unmodified

Gene Information

human ... H2AFZ(3015)

General description

16kDa

Immunogen

peptide containing the sequence SLIGKKGQQ, corres-ponding to the C-terminus of human histone H2A.Z

Application

Detect Histone H2A.Z also known as H2AZ histone with Anti-Histone H2A.Z Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Biochem/physiol Actions

Broad species cross-reactivity is expected
C-terminus of histone H2A.Z

Physical form

0.05% sodium azide before the addition of glycerol to 30%
Serum

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on acid extracted proteins from HeLa cells and recombinant Histone H2A.Z (Catalog #14-597), no cross-reactivity with Histone H2A

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zenab F Mchaourab et al.
Scientific data, 5, 180030-180030 (2018-03-07)
The human K562 chronic myeloid leukemia cell line has long served as an experimental paradigm for functional genomic studies. To systematically and functionally annotate the human genome, the ENCODE consortium generated hundreds of functional genomic data sets, such as chromatin
Characterization of the stability and folding of H2A.Z chromatin particles: implications for transcriptional activation.
Abbott, D W, et al.
The Journal of Biological Chemistry, 276, 41945-41949 (2001)
Molecular cloaking of H2A.Z on mortal DNA chromosomes during nonrandom segregation.
Yang Hoon Huh,James L Sherley
Stem Cells null
Chunyuan Jin et al.
Nature genetics, 41(8), 941-945 (2009-07-28)
To understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human cells. We find that a special class of NCPs
Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression.
Hua, S; Kallen, CB; Dhar, R; Baquero, MT; Mason, CE; Russell, BA; Shah, PK; Liu et al.
Molecular Systems Biology null

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