07-790
Anti-phospho-PKCα (Ser657/Tyr658) Antibody
Upstate®, from rabbit
Synonym(s):
PRKCA, PKC-alpha, PKCA, PRKACA
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IP, WB
Citations:
11
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, rat, rabbit
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pSer657/pTyr658)
Gene Information
human ... PRKCA(5578)
General description
82 kDa
Immunogen
KLH conjugated peptide corresponding to amino acid region encompassing the human phospho-PKCα (Ser657/Tyr658).
Application
Anti-phospho-PKCα (Ser657/Tyr658) Antibody detects level of phospho-PKCα (Ser657/Tyr658) & has been published & validated for use in ELISA, IP & WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Enzymes & Biochemistry
Enzymes & Biochemistry
Biochem/physiol Actions
Recognizes phospho-PKCα (Ser657/Tyr658). This sequence is similar to PKCβI (Ser661/Tyr662) and PKCγ (Thr674/Tyr675).
Physical form
ImmunoAffinity Purified
Analysis Note
Routinely evaluated by immunoblot.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle
Somara, Sita and Bitar, Khalil N
American Journal of Physiology: Gastrointestinal and Liver Physiology, 291, G630-G639 (2006)
Haoran Miao et al.
Oncology reports, 48(6) (2022-10-26)
Current investigations suggest that pigment epithelial‑derived factor (PEDF) can mediate the progression of non‑small cell lung cancer (NSCLC) by regulating autophagy. However, the underlying mechanisms associated with autophagy remain poorly elucidated. The aim of the present study was to investigate
Zangbéwendé Guy Ouédraogo et al.
Brain pathology (Zurich, Switzerland), 26(1), 18-30 (2015-03-05)
Radiotherapy is an essential component of glioma standard treatment. Glioblastomas (GBM), however, display an important radioresistance leading to tumor recurrence. To improve patient prognosis, there is a need to radiosensitize GBM cells and to circumvent the mechanisms of resistance caused
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 07-790 | 04053252506772 |