PADI4 (Protein-arginine deiminase type-4) is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalysis of the deimination of the arginine residues. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.

~74 kDa

The antibody recognizes PADI4 at and around the C-terminus.

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of PADI4.

Anti-PADI4 Antibody, C-terminus is an antibody against PADI4 for use in WB, ELISA.

ELISA: A 1:1000 dilution of a previous lot was used on ELISA.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Stable for 6 months at 2-8ºC from date of receipt. For long term storage, store at -20ºC

Control
HEK293 cell lysate

Evaluated by western blot on HEK293 cell lysate.

Western Blotting Analysis: 1:25-1:500 dilution of this antibody detected PADI4 in HEK293 cell lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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