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Merck
CN

100107

4-Bromo-calcium Ionophore A23187

≥90% (HPLC), solid, cation ionophore, Calbiochem®

Synonym(s):

4-Bromo-A23187, 4-Bromo-calcimycin

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About This Item

Empirical Formula (Hill Notation):
C29H36BrN3O6
CAS Number:
Molecular Weight:
602.52
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
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Product Name

4-Bromo-calcium Ionophore A23187, Brominated analog of the widely used cation ionophore A23187. Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

InChI

1S/C29H36BrN3O6/c1-14-8-9-29(16(3)11-15(2)27(39-29)17(4)26(34)19-7-6-10-32-19)38-20(14)13-22-33-25-21(37-22)12-18(30)24(31-5)23(25)28(35)36/h6-7,10,12,14-17,20,27,31-32H,8-9,11,13H2,1-5H3,(H,35,36)/t14-,15-,16-,17-,20-,27+,29+/m1/s1

SMILES string

CNc1c(Br)cc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(O)=O

InChI key

LDXQFZZGVTWFCF-FHYGWRBKSA-N

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

yellow

solubility

DMSO: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

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Application

Nonfluorescent Ca2+ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca2+ with fluorescent probes.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Cation ionophore
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Harmful (C)

General description

Brominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

Other Notes

Deber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.
Deber, C.M., et al. 1985. Anal. Biochem.146, 349.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
This item has

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