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100107

4-Bromo-calcium Ionophore A23187

Name: 4-Bromo-calcium Ionophore A23187
Brand: MM

≥90% (HPLC), solid, cation ionophore, Calbiochem^®

Synonym(s):

4-Bromo-A23187, 4-Bromo-calcimycin

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About This Item

Empirical Formula (Hill Notation):

C₂₉H₃₆BrN₃O₆

CAS Number:

76455-48-6

Molecular Weight:

602.52

NACRES:

NA.77

UNSPSC Code:

12352200

MDL number:

MFCD00077667

Assay:

≥90% (HPLC)

Form:

solid

Storage condition:

OK to freeze, desiccated (hygroscopic), protect from light

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Properties

Product Name

4-Bromo-calcium Ionophore A23187, Brominated analog of the widely used cation ionophore A23187. Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

Quality Segment

100

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

color

yellow

solubility

DMSO: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

CNc1c(Br)cc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(O)=O

InChI

1S/C29H36BrN3O6/c1-14-8-9-29(16(3)11-15(2)27(39-29)17(4)26(34)19-7-6-10-32-19)38-20(14)13-22-33-25-21(37-22)12-18(30)24(31-5)23(25)28(35)36/h6-7,10,12,14-17,20,27,31-32H,8-9,11,13H2,1-5H3,(H,35,36)/t14-,15-,16-,17-,20-,27+,29+/m1/s1

InChI key

LDXQFZZGVTWFCF-FHYGWRBKSA-N

Description

General description

Brominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

Application

Nonfluorescent Ca²⁺ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca²⁺ with fluorescent probes.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Cation ionophore

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Other Notes

Deber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.
Deber, C.M., et al. 1985. Anal. Biochem.146, 349.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c