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1.02445

Supelco

Chloroform

for analysis EMSURE® ACS,ISO,Reag. Ph Eur

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Synonym(s):
TCM, Trichloromethane, Methane trichloride, Methyl trichloride, Methylidyne trichloride, Trichloromethane
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
67-66-3
Molecular Weight:
119.38
Beilstein:
1731042
MDL number:
MFCD00000826
EC Index Number:
200-663-8

grade

ACS reagent

Quality Level

300

Agency

reag. ISO
reag. Ph. Eur.

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

product line

EMSURE®

Assay

≥99.8%
90-99.4% (GC)

form

liquid

potency

695 mg/kg LD50, oral (Rat)
>3980 mg/kg LD50, skin (Rabbit)

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

storage temp.

2-30°C

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

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General description

EMSURE grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE provides worldwide best and most extensive product specifications. We declare our EMSURE range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.

Application

Chloroform is used as a:
  • Solvent in the lipid analysis process to dissolve isolated lipid samples.
  • Component of the solvent mixture used for the extraction and purification of DNA from homogenized liver tissue.

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

监管及禁止进口产品

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Differential expression of genes and DNA methylation associated with prenatal protein undernutrition by albumen removal in an avian model
Els W, et al.
Scientific Reports, 6, 20837-20837 (2016)
Direct lipid extraction from wet Chlamydomonas reinhardtii biomass using osmotic shock
Gursong Y et al.
Bioresource Technology, 123, 717-722 (2012)
Lihua Song et al.
Journal of medicinal food, 23(2), 161-172 (2020-01-09)
Both serum and hepatic fatty acid (FA) compositions differ among nonalcoholic hepatic steatosis, nonalcoholic steatohepatitis, and healthy subjects. The severity of the above liver disease is closely associated with the concentration and composition of FAs. Our previous study found that

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Titration of hydrocarbons may require solubilizers for unpolar substances; recommend long-chain alcohols or chloroform.

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