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Merck
CN

1.06022

Sodium dodecyl sulfate

for biochemistry 10% in H2O

Synonym(s):

Dodecyl sulfate sodium salt, SDS, Lauryl sulfate sodium salt, Dodecyl sodium sulfate

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About This Item

NACRES:
NC.01
UNSPSC Code:
12352107

Key Documents

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Product Name

Sodium dodecyl sulfate, for biochemistry 10% in H2O

form

liquid

pH

9 (20 °C in H2O)

density

1.012 g/cm3 at 20 °C

storage temp.

15-25°C

Quality Level

100

Related Categories

General description

Dodecyl sulfate sodium or sodium dodecyl sulfate (SDS) is an ionic detergent comprising a polar sulfate head group and a hydrophobic 12-carbon chain.

Analysis Note

Assay (two-phase titration): 9.8 - 10.2 %

Biochem/physiol Actions

Dodecyl sulfate sodium or sodium dodecyl sulfate (SDS) combines effectively with the positively charged and hydrophobic residues of proteins using sulfate groups and alkyl chains. This detergent is very valuable in the field of structural biology and protein folding/unfolding studies. SDS can initiate the generation of α-helices in a protein structure. It stimulates cooperative unfolding in proteins like bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Protocols

Cell Lysis and Protein Extraction for Western Blotting

Protocol for sample preparation for cell lysis and efficient protein extraction from cultured tissues and cells for subsequent Western blotting.

WB检测样本前处理：细胞裂解和蛋白提取

Western blotting前用于培养组织和细胞的细胞裂解和有效蛋白提取的样品制备实验方案。

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