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Merck
CN

1.06146

Isobutyl methyl ketone

for extraction analysis EMSURE® ACS,Reag. Ph Eur

Synonym(s):

4-Methyl-2-pentanone, Isobutyl methyl ketone, Isopropylacetone, MIBK, Methyl isobutyl ketone

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About This Item

Linear Formula:
(CH3)2CHCH2COCH3
CAS Number:
Molecular Weight:
100.16
UNSPSC Code:
12191502
NACRES:
NA.05
EC Index Number:
203-550-1
MDL number:
Beilstein/REAXYS Number:
605399
Assay:
≥99% (GC)
Grade:
ACS reagent
Bp:
117-118 °C
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grade

ACS reagent

Quality Level

agency

reag. Ph. Eur.

vapor density

3.5 (vs air)

product line

EMSURE®

assay

≥99% (GC)

form

liquid

autoignition temp.

840 °F

potency

2080 mg/kg LD50, oral (Rat), >16000 mg/kg LD50, skin (Rabbit)

expl. lim.

1.2-8 %, 93 °F

dilution

(for analytical testing)

impurities

≤0.00005% Al (Aluminium), ≤0.001 meq/g Alkalinity, ≤0.002 meq/g Titrable acid, ≤0.1% Water

evapn. residue

≤0.0010%

color

clearAPHA: ≤10

refractive index

n20/D 1.395 (lit.)

pH

7 (20 °C)

bp

117-118 °C

mp

−80 °C (lit.)

transition temp

flash point 14 °C

density

0.801 g/mL at 25 °C (lit.)

cation traces

B: ≤0.000002%, Ba: ≤0.00001%, Ca: ≤0.00005%, Cd: ≤0.000005%, Co: ≤0.000002%, Cr: ≤0.000002%, Cu: ≤0.000002%, Fe: ≤0.00001%, Mg: ≤0.00001%, Mn: ≤0.000002%, Ni: ≤0.000002%, Pb: ≤0.00001%, Sn: ≤0.00001%, Zn: ≤0.00001%

storage temp.

2-30°C

SMILES string

CC(C)CC(C)=O

InChI

1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3

InChI key

NTIZESTWPVYFNL-UHFFFAOYSA-N

General description

EMSURE grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE provides worldwide best and most extensive product specifications. We declare our EMSURE range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.

Application


  • Determination of cadmium in biological samples by inductively coupled plasma atomic emission spectrometry after extraction with 1,5-bis(di-2-pyridylmethylene) thiocarbonohydrazide.: This study utilizes Isobutyl methyl ketone (IBMK) as a solvent in the extraction process for determining cadmium in biological samples. The research highlights the efficacy of IBMK in enhancing the sensitivity and accuracy of inductively coupled plasma atomic emission spectrometry (ICP-AES), crucial for trace metal analysis in various biological and environmental samples (Espinosa Almendro et al., 1992).

  • Colorimetric determination of acetylenic hypnotics by formation of silver acetylides.: This research demonstrates a colorimetric method for determining acetylenic hypnotics using Isobutyl methyl ketone (IBMK) as a solvent. IBMK is instrumental in the formation of silver acetylides, facilitating the detection and quantification of these compounds in pharmaceutical formulations. The study underscores the versatility of IBMK in analytical chemistry applications, particularly in the pharmaceutical industry (Rizk et al., 1980).


Other Notes

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Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Carc. 2 Inhalation - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F - closed cup

flash_point_c

14 °C - closed cup

Regulatory Information

危险化学品

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Global Trade Item Number

SKUGTIN
106146400004027269683962
106146602504022536073361
106146100004022536073316
106146250004022536073330