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Merck
CN

1.06370

Sodium dihydrogen phosphate

anhydrous 99.99 Suprapur®

Synonym(s):

Sodium dihydrogen phosphate, Sodium biphosphate

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About This Item

Empirical Formula (Hill Notation):
H2NaO4P
CAS Number:
Molecular Weight:
119.98
UNSPSC Code:
12352302
EC Index Number:
231-449-2
NACRES:
NA.21
MDL number:
Assay:
99.99%
Form:
crystals
Solubility:
850 g/L
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Quality Segment

description

for inorganic trace analysis

assay

99.99%

form

crystals

potency

8290 mg/kg LD50, oral (Rat), >7940 mg/kg LD50, skin (Rabbit)

pH

4.5 (20 °C, 10 g/L in H2O)

mp

>450 °C ((> 842 °F))

solubility

850 g/L

bulk density

940 kg/m3

anion traces

chloride (Cl-): ≤5 ppm, sulfate (SO42-): ≤30 ppm

cation traces

As: ≤0.05 ppm, Ba: ≤10.0 ppm, Ca: ≤0.50 ppm, Cd: ≤0.010 ppm, Ce: ≤0.010 ppm, Co: ≤0.010 ppm, Cs: ≤5 ppm, Cu: ≤0.010 ppm, Eu: ≤0.010 ppm, Fe: ≤0.05 ppm, Hg: ≤0.05 ppm, K: ≤5.0 ppm, La: ≤0.010 ppm, Li: ≤1.0 ppm, Mg: ≤0.50 ppm, Mn: ≤0.010 ppm, N: ≤10 ppm, Ni: ≤0.010 ppm, Pb: ≤0.010 ppm, Rb: ≤5.0 ppm, Sm: ≤0.010 ppm, Sr: ≤0.50 ppm, Tl: ≤0.01 ppm, Y: ≤0.010 ppm, Yb: ≤0.010 ppm, Zn: ≤0.010 ppm

storage temp.

2-30°C

SMILES string

[Na+].[P](=O)([O-])([O-])[O-].[H+].[H+]

InChI

1S/Na.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

AJPJDKMHJJGVTQ-UHFFFAOYSA-M

Application


  • Development of a multiparticulate drug delivery system for in situ amorphisation.: This study explores the creation of a multiparticulate drug delivery system using sodium dihydrogen phosphate to induce in situ amorphisation, enhancing the bioavailability of poorly water-soluble drugs (Holm et al., 2022).

Analysis Note

Purity (metallic): ≥ 99.99 %
Assay (acidimetric): ≥ 99.0 %
Spec. Absorbance A at 260 nm (2 cm; 10 %): ≤ 0.020
Chloride (Cl): ≤ 5 ppm
Sulfate (SO₄): ≤ 30 ppm
Total nitrogen (N): ≤ 10 ppm
As (Arsenic): ≤ 0.05 ppm
Ba (Barium): ≤ 10.0 ppm
Ca (Calcium): ≤ 0.50 ppm
Cd (Cadmium): ≤ 0.010 ppm
Ce (Cerium): ≤ 0.010 ppm
Co (Cobalt): ≤ 0.010 ppm
Cs (Cesium): ≤ 5 ppm
Cu (Copper): ≤ 0.010 ppm
Eu (Europium): ≤ 0.010 ppm
Fe (Iron): ≤ 0.05 ppm
Hg (Mercury): ≤ 0.05 ppm
K (Potassium): ≤ 5.0 ppm
La (Lanthanum): ≤ 0.010 ppm
Li (Lithium): ≤ 1.0 ppm
Mg (Magnesium): ≤ 0.50 ppm
Mn (Manganese): ≤ 0.010 ppm
Ni (Nickel): ≤ 0.010 ppm
Pb (Lead): ≤ 0.010 ppm
Rb (Rubidium): ≤ 5.0 ppm
Sm (Samarium): ≤ 0.010 ppm
Sr (Strontium): ≤ 0.50 ppm
Tl (Thallium): ≤ 0.01 ppm
Y (Yttrium): ≤ 0.010 ppm
Yb (Ytterbium): ≤ 0.010 ppm
Zn (Zinc): ≤ 0.010 ppm

Legal Information

SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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