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1.15333

Supelco

Water

for chromatography (LC-MS Grade) LiChrosolv®

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Synonym(s):
Deionized water, Distilled Water
Linear Formula:
H2O
CAS Number:
Molecular Weight:
18.02
Beilstein:
2050024
MDL number:

vapor pressure

23 hPa ( 20 °C)

Quality Level

product line

LiChrosolv®

form

liquid

technique(s)

LC/MS: suitable

refractive index

n20/D 1.34 (lit.)

pH

7 (20 °C)

bp

100 °C (lit.)

mp

0 °C (lit.)

density

1.000 g/mL at 3.98 °C (lit.)

storage temp.

2-30°C

SMILES string

O

InChI

1S/H2O/h1H2

InChI key

XLYOFNOQVPJJNP-UHFFFAOYSA-N

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General description

LiChrosolv® solvents have high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Application

Intended for U/HPLC and LC-MS applications.
Also featured in:
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Features and Benefits

  • Microfiltered by 0.2 µm filter
  • Packaged in glass bottles
  • Offers high resolution, sensitivity and optimized peak baseline separation
  • Provides rapid and reliable results in both electrospray ionization/atmospheric pressure chemical ionization (ESI/APCI) positive and negative ionization modes

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Optimization of a Reversed-Phase Liquid Chromatographic (RP-LC) method for the intact analysis of a therapeutic monoclonal antibody, trastuzumab, using a BIOshell™ A400 Protein C4 column.

Development of an HPLC-UV method to determine Arbutin and Hydroquinone in whitening serum using a Chromolith® HighResolution C18 100x2mm HPLC column.

A new HPLC-RI method is proposed for the analysis of Lactose in milk using a Chromolith® NH2 column.

The article describes the use of difluoroacetic acid (DFA) as an effective alternative to acid modifiers, formic acid (FA) and trifluoroacetic acid (TFA) in the LC-UV/MS analysis of proteins.

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Protocols

Bispecific antibodies are a new class of biotherapeutics where one therapeutic agent can target two different antigens. This application note demonstrates a new size exclusion chromatographic method for characterizing these new biotherapeutics by mass spectrometry.

Thin layer chromatography coupled with mass spectrometry does not require substantial sample preparation. Energy drinks can be applied without dilution directly onto the TLC plate.

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A rapid, accurate, and simple method was implemented for the total chromatographic purity analysis of Fingolimod Hydrochloride by High-Performance Liquid Chromatography equipped with a Diode Array Detector.

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