12-523
GST, 6 His-tagged
Synonym(s):
GST Fusion Protein
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About This Item
UNSPSC Code:
12352204
NACRES:
NA.41
eCl@ss:
32160405
form
liquid
Quality Level
manufacturer/tradename
Upstate®
technique(s)
affinity chromatography: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
Glutathione S-transferase (GST) belongs to three families of proteins distinguished as cytosolic, mitochondrial, and microsomal GST. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α, κ, μ, ω, π, σ, θ, and ζ. This product is a C-terminal 6 histidine-tagged, recombinant full-length glutathione S-transferase (GST).
Biochem/physiol Actions
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in phase II detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Physical form
50mM Tris-HCl, pH 8, 150mM NaCl, 20% glycerol
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 2
Certificates of Analysis (COA)
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