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Merck
CN

14-909-M

MELK Protein, active, 0 0

Active, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.

Synonym(s):

HPK38, PK38, pEg3 kinase

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
human
Recombinant:
expressed in baculovirus infected insect cells
Mol wt:
Mw 66 kDa

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Product Name

MELK Protein, active, 0 0, Active, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.

biological source

human

recombinant

expressed in baculovirus infected insect cells

mol wt

Mw 66 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

UniProt accession no.

Q14680

Quality Level

300

Gene Information

human ... MELK(9833)

Biochem/physiol Actions

Target Sub-Family: CAMK

Analysis Note

Routinely evaluated by phosphorylation of KKLNRTLSFAEPG

Application

Research Category
Signaling

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Product Source: Recombinant protein of the human MELK gene expressed by baculovirus in insect cells
Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Packaging

Also available in 250μg size - call for pricing and availability and reference catalog number 14-909M when ordering the 250μg size

Physical form

Purified using glutathione-agarose

Preparation Note

6 months at -70°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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