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1.59002

Supelco

Acetonitrile with 0.1% (v/v) Formic acid

hypergrade for LC-MS LiChrosolv®

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Synonym(s):
Acetonitrile solution
Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein:
4124158
MDL number:

vapor pressure

97 hPa ( 20 °C)

Quality Level

product line

LiChrosolv®

form

liquid

concentration

0.095-0.105 % (v/v)

technique(s)

LC/MS: suitable

bp

81.6 °C/1,013 hPa

mp

-45.7 °C

transition temp

flash point 2 °C

density

0.782 g/mL at 25 °C

format

mixture

storage temp.

2-30°C

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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General description

For fast chromatography and LC-MS detection, LiChrosolv® hypergrade, a family of solvents especially optimized and tested for LC-MS suitability is most suitable. LiChrosolv® hypergrade solvents meet all the requirements of modern LC-MS ionization methods (ESI/ APCI – positive and negative mode). Due to their low level of ionic background and low ion suppression, LiChrosolv® hypergrade solvents ensure high reproducibility and high ionization efficiency.

Application

LiChrosolv® hypergrade acetonitrile with 0.1% (v/v) formic acid is used as a mobile phase solvent in gradient elution of peptides by LC-MS/MS.
The product is also featured in the method development for analysis of California list of pesticides in cannabis.

Features and Benefits

  • microfiltered by 0.2 µm filter
  • the most comprehensive application range due to the largest retention time range
  • analytical reliability due to the highest possible purity and a minimum signal-to-noise ratio
  • time and cost savings due to the best possible batch consistency, thus avoiding repetitive analysis

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

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Description
Pricing

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - (refers to pure substance)

Flash Point(C)

2 °C - (refers to pure substance)

Regulatory Information

危险化学品

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Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Alzahofi N, et al.
Nature Communications, 11(1), 1-21 (2020)
The stereospecific interaction sites and target specificity of cGMP analogs in mouse cortex
Rasmussen M, et al.
Chemical Biology & Drug Design, 99(2), 206-221 (2022)
The cGMP system in normal and degenerating mouse neuroretina: New proteins with cGMP interaction potential identified by a proteomics approach
Rasmussen M, et al.
Journal of Neurochemistry, 157(6), 2173-2186 (2021)

Articles

An optimized peptide mapping protocol using NISTmAb as a model monoclonal antibody, shorter incubation times, and improved digestion buffer to demonstrate minimal artificial asparagine deamidation and methionine oxidation.

Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.

To show product safety, it is mandatory to test cannabis flowers for the presence of pesticides. In this article, we show a complete workflow for sample preparation and analysis of cannabis for the pesticides registered in California, by LC-MS/MS and GC-MS/MS

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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