1.59014
97 hPa ( 20 °C)
LiChrosolv®
liquid
0.095-0.105 % (v/v)
LC/MS: suitable
≤0.025 ppm K (Potassium)
≤0.05 ppm Al (Aluminium)
≤0.05 ppm Ca (Calcium)
≤0.05 ppm Fe (Iron)
≤0.05 ppm Mg (Magnesium)
≤0.25 ppm Na (Sodium)
APHA: ≤10
flash point 2 °C
0.782 g/mL at 25 °C
mixture
2-30°C
CC#N
1S/C2H3N/c1-2-3/h1H3
WEVYAHXRMPXWCK-UHFFFAOYSA-N
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Danger
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
3 - Flammable liquids
WGK 2
35.6 °F - (Acetonitrile)
2 °C - (Acetonitrile)
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Determination of plasma protein binding using a SupelTM C18 pin device based BioSPME method for efficient sample preparation, along with a comparison to the equilibrium dialysis method.
Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.
The application note describes a comparative analysis of plasma protein binding results for free/bound drugs using two different sample extraction steps, with and without agitation.
Learn about Supel™ BioSPME C18 high-throughput devices to determine plasma protein binding and decrease the sample preparation time to less than an hour.
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