Key Documents

View All Documentation

165304

D-(–)-2-Amino-5-phosphonopentanoic Acid

Name: D-(&#8211;)-2-Amino-5-phosphonopentanoic Acid
Brand: MM

≥97% (HPLC), solid, NMDA receptor antagonist, Calbiochem^®

Synonym(s):

D-(–)-2-Amino-5-phosphonopentanoic Acid, D-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₅H₁₂NO₅P

CAS Number:

79055-68-8

Molecular Weight:

197.13

UNSPSC Code:

12352106

NACRES:

NA.77

MDL number:

MFCD00078839

Assay:

≥97% (HPLC)

Form:

solid

Storage condition:

OK to freeze, desiccated (hygroscopic), protect from light

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

D-(–)-2-Amino-5-phosphonopentanoic Acid, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.

Quality Segment

100

assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

color

white

solubility

dilute aqueous base: 1 mg/mL, water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[P](=O)([O-])([O-])CCC[C@@H]([N+H3])C(=O)[O-]

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1

InChI key

VOROEQBFPPIACJ-SCSAIBSYSA-L

Description

General description

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.

Biochem/physiol Actions

Cell permeable: no

Primary Target
NMDA receptor antagonist

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
Schulte, M.K., et al. 1994. Brain Res. 649, 203.
Davis, S., et al. 1992. J. Neurosci. 12, 21.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Still not finding the right product?

Explore all of our products under D-(–)-2-Amino-5-phosphonopentanoic Acid

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c