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Merck
CN

172103

Anaphase-Promoting Complex Inhibitor Negative Control, AAME

The Anaphase-Promoting Complex Inhibitor Negative Control, AAME, also referenced under CAS 1784-05-0, controls the biological activity of Anaphase-Promoting Complex.

Synonym(s):

Anaphase-Promoting Complex Inhibitor Negative Control, AAME, AAME hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H18N4O3 · xHCl
CAS Number:
Molecular Weight:
230.26 (free base basis)
MDL number:
UNSPSC Code:
41106609
NACRES:
NA.77
Assay:
≥99% (TLC)
Form:
powder
Quality level:
Storage condition:
OK to freeze, protect from light
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Quality Level

assay

≥99% (TLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

water: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

N=C(NCCC[C@@H](C(OC)=O)NC(C)=O)N.[xHCl]

InChI

1S/C9H18N4O3.ClH/c1-6(14)13-7(8(15)16-2)4-3-5-12-9(10)11;/h7H,3-5H2,1-2H3,(H,13,14)(H4,10,11,12);1H/t7-;/m0./s1

InChI key

FIUSXBMWQFBXLZ-FJXQXJEOSA-N

General description

An acetyl-L-arginine analog of TAME that serves as a negative control. TAME is an ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Zeng, X., et al. 2010. Cancer Cell18, 382.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Regulatory Review (Z)


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
172103-50MG04055977222890