176871
Angiotensin Converting Enzyme, His Tag , Human, Recombinant, NSO Cells
Synonym(s):
Hypertensinogen, Renin Substrate
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About This Item
NACRES:
NA.28
UNSPSC Code:
12352200
Form:
liquid
Storage condition:
OK to freeze
form
liquid
Quality Segment
specific activity
≥1 unit/µg protein
storage condition
OK to freeze
storage temp.
−70°C
General description
Recombinant, human ACE ectodomain (amino acids 30-1261) fused at the C-terminus to a HIS TAG® sequence and expressed in NSO cells. ACE is a zinc metallopeptidase that cleaves the C-terminal dipeptide from angiotensin I to produce the potent vasopressor octapeptide angiotensin II. ACE gene polymorphism has been a recent topic in Alzheimer′s disease studies. ACE is a type I membrane protein and exists in two isoforms, somatic and germinal. By SDS-PAGE, the apparent molecular weight of the glycosylated protein appears larger to be than 120 kDa under both reducing and non-reducing conditions.
Legal Information
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Certificates of Analysis (COA)
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