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189482

Autocamtide-2 Related Inhibitory Peptide, Myristoylated

Name: Autocamtide-2 Related Inhibitory Peptide, Myristoylated
Brand: MM

≥97% (HPLC), CaM kinase II inhibitor, lyophilized

Synonym(s):

Autocamtide-2 Related Inhibitory Peptide, Myristoylated, Myristoylated AIP, Myr-N-KKALRRQGAVDAL-OH

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About This Item

Empirical Formula (Hill Notation):

C₇₈H₁₄₂N₂₂O₂₀

Molecular Weight:

1708.10

UNSPSC Code:

12352202

NACRES:

NA.77

Assay:

≥97% (HPLC)

Form:

lyophilized

Quality level:

100

Storage condition:

OK to freeze, desiccated (hygroscopic)

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Properties

Product Name

Autocamtide-2 Related Inhibitory Peptide, Myristoylated, The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Quality Level

100

assay

≥97% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

Description

General description

This peptide corresponds to AIP (Cat. No. 189480 ) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Calmodulin-Dependent Protein Kinase (CaM Kinase)-2

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 40 nM against cam Kinase-2

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Gailly, P., et al. 1998. Cell Calcium 24, 293.
Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.
Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.

Myr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c