204870-M
Complement C3d, Human
Complement C3d, Human is a native, 30 kDa polypeptide formed by the limited digestion of iC3b by trypsin or elastin. The binding of C3d to CR2 on B lymphocytes enhances B cell activation.
Synonym(s):
Complement Protein
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.25
assay
≥85% (SDS-PAGE)
form
liquid
does not contain
preservative
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
impurities
IgG, IgM, IgA, C5, Factor H, Factor I, trace
storage temp.
−70°C
Quality Level
General description
Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.
Physical form
In PBS, pH 7.2.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol.153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA82, 4235.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA82, 4235.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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