204881
Complement C3a Peptide
≥95% (SDS-PAGE), liquid, human
Synonym(s):
C3a Protein
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.77
Product Name
Complement C3a, Human, Complement C3a, Human, is a native, single chain C3a complement component. It has many biological activities, such as smooth muscle contraction, platelet activation, & immunoregulatory reactions.
Quality Level
assay
≥95% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
impurities
≤10% C3adesArg
shipped in
wet ice
storage temp.
−70°C
General description
Native, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzyme (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77, resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities, which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Hugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
Hugli, T.E. 1986. Complement 3, 111.
Hugli, T.E. 1986. Complement 3, 111.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 204881-50UG | 04055977219746 |