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Merck
CN

208698-M

Calmodulin, Human Brain

Calmodulin, Human Brain, is a ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from human brain.

Synonym(s):

CaM, Ca 2+/Calmodulin, CaM, Ca2+/Calmodulin

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.25
Form:
lyophilized
Assay:
≥95% (native PAGE)
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assay

≥95% (native PAGE)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

storage temp.

−20°C

Quality Level

General description

Calmodulin purifed from human brain.
Calmodulin purifed from human brain. Calmodulin is a ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate.

Physical form

Lyophilized from protein solution with 2 mM EDTA.

Preparation Note

Reconstitute with distilled water. H₂O (1 mg/ml)

Other Notes

O′Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci.15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun.104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.
One unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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