217503
Cardiotoxin
from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®
Synonym(s):
Cardiotoxin, Naja pallida
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About This Item
Product Name
Cardiotoxin, Naja pallida,
description
Merck USA index - 14, 1835
Quality Level
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.
Application
Cardiotoxin, Naja pallida has been used:
- to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration
- to induce a skeletal muscle injury into the right TA muscle
- to induce muscle regeneration
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.
Legal Information
Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
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Chen J, et al.
Cell Death & Disease, 15(3), 201-201 (2024)
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Harvey, Alan L
Handbook of Biologically Active Peptides (2013)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 217503-1MG | 04055977276800 |