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218735

Caspase Inhibitor II

Name: Caspase Inhibitor II
Brand: MM

The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.

Synonym(s):

Caspase Inhibitor II, Ac-VAD-CHO

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₃N₃O₆

CAS Number:

147837-52-3

Molecular Weight:

329.35

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00672421

Assay:

≥95% (HPLC)

Form:

solid

Storage condition:

OK to freeze

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Properties

Quality Segment

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

DMSO: 150 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

N([C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)C(C)C)C

InChI

1S/C14H23N3O6/c1-7(2)12(16-9(4)19)14(23)15-8(3)13(22)17-10(6-18)5-11(20)21/h6-8,10,12H,5H2,1-4H3,(H,15,23)(H,16,19)(H,17,22)(H,20,21)/t8-,10-,12-/m0/s1

InChI key

BGFYQRSQECIBIB-PEXQALLHSA-N

Description

General description

A potent and reversible inhibitor of caspases.

A potent and reversible pan-caspase inhibitor.

Biochem/physiol Actions

Cell permeable: no

Primary Target
pan-caspase

Product does not compete with ATP.

Reversible: yes

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Val-Ala-Asp-CHO

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c