218739
Caspase-1 Substrate X, Fluorogenic
A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.
Synonym(s):
Caspase-1 Substrate X, Fluorogenic, Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
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About This Item
Empirical Formula (Hill Notation):
C38H40N8O11
CAS Number:
Molecular Weight:
784.77
MDL number:
NACRES:
NA.54
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
lyophilized
Storage condition:
OK to freeze, desiccated, protect from light
Quality Segment
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
solubility
DMSO: 5 mg/mL
fluorescence
λex 365–380 nm, λem 430–460 nm
shipped in
ambient
storage temp.
−20°C
General description
A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: no
Other Notes
Ac-Trp-Glu-His-Asp-AMC
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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