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218744

Caspase-2 Inhibitor I

Name: Caspase-2 Inhibitor I
Brand: MM

The Caspase-2 Inhibitor I controls the biological activity of Caspase-2. This small molecule/inhibitor is primarily used for Cancer applications.

Synonym(s):

Caspase-2 Inhibitor I, Z-VD(OMe)VAD(OMe)-FMK

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About This Item

Empirical Formula (Hill Notation):

C₃₂H₄₆FN₅O₁₁

Molecular Weight:

695.73

NACRES:

NA.54

UNSPSC Code:

12352200

Assay:

≥95% (HPLC), ≥95% (TLC)

Form:

lyophilized

Storage condition:

OK to freeze, desiccated

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Properties

Quality Segment

100

assay

≥95% (HPLC), ≥95% (TLC)

form

lyophilized

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

Description

General description

A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1)

An irreversible inhibitor of caspase-2 (ICH-1).

Biochem/physiol Actions

Cell permeable: yes

Primary Target
caspase-2

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-CH₂F*

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c