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Caspase-4 Inhibitor I

Name: Caspase-4 Inhibitor I
Brand: MM

The Caspase-4 Inhibitor I, also referenced under CAS 402832-01-3, controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.

Synonym(s):

Caspase-4 Inhibitor I, Ac-LEVD-CHO

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₆N₄O₉

CAS Number:

402832-01-3

Molecular Weight:

500.54

MDL number:

MFCD08703162

UNSPSC Code:

12352200

NACRES:

NA.54

Assay:

≥95% (HPLC)

Form:

lyophilized solid

Storage condition:

OK to freeze

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Properties

Quality Segment

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

N([C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)CCC(=O)O

InChI

1S/C22H36N4O9/c1-11(2)8-16(23-13(5)28)21(34)25-15(6-7-17(29)30)20(33)26-19(12(3)4)22(35)24-14(10-27)9-18(31)32/h10-12,14-16,19H,6-9H2,1-5H3,(H,23,28)(H,24,35)(H,25,34)(H,26,33)(H,29,30)(H,31,32)/t14-,15-,16-,19-/m0/s1

InChI key

MXGJLIBJKIIQSF-FPXQBCRKSA-N

Description

General description

A reversible caspase-4 (ICH-2) inhibitor.

A reversible caspase-4 inhibitor.

Biochem/physiol Actions

Cell permeable: no

Primary Target
caspase-4

Product does not compete with ATP.

Reversible: yes

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Leu-Glu-Val-Asp-CHO

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c