218757
Caspase-6 Inhibitor I
The Caspase-6 Inhibitor I controls the biological activity of Caspase-6. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase-6 Inhibitor I, Z-VE(OMe)ID(OMe)-FMK
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About This Item
Empirical Formula (Hill Notation):
C31H45FN4O10
Molecular Weight:
652.71
UNSPSC Code:
12352200
Assay:
≥90% (TLC)
Form:
lyophilized solid
Storage condition:
OK to freeze, desiccated
Quality Segment
assay
≥90% (TLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A cell-permeable, irreversible inhibitor of caspase-6. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
caspase-6
caspase-6
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Z-Val-Glu(OMe)-Ile-Asp(OMe)-CH₂F*
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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