218766-M
Caspase-4 Inhibitor I, Cell-Permeable
The Caspase-4 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase-4 Inhibitor I, Cell-Permeable, LEVD-CHO, Cell-permeable; sequence
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About This Item
Empirical Formula (Hill Notation):
C96H164N20O25
Molecular Weight:
1998.45
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥97% (HPLC)
Form:
lyophilized powder
Storage condition:
OK to freeze
assay
≥97% (HPLC)
form
lyophilized powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
DMSO: 5 mg/mL
storage temp.
−20°C
General description
A potent, cell-permeable, and reversible inhibitor of caspase-4. The N-terminal sequence (amino acid residues 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
Potent, cell-permeable and reversible inhibitor of caspase-4.
Biochem/physiol Actions
Primary Target
caspase-4
caspase-4
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-Val-Asp-CHO
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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