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Merck
CN

239785

Cyclophosphamide Monohydrate

≥98% (HPLC), solid, anti-neoplastic agent, Calbiochem®

Synonym(s):

Cyclophosphamide Monohydrate, N,N- bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA, N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA

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About This Item

Empirical Formula (Hill Notation):
C7H15Cl2N2O2P · xH2O
CAS Number:
6055-19-2
Molecular Weight:
261.09 (anhydrous basis)
UNSPSC Code:
51112507
NACRES:
NA.77
MDL number:
MFCD00149395

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Product Name

Cyclophosphamide Monohydrate, A widely used anti-neoplastic agent that also displays immunosuppressant properties.

SMILES string

[P]1(=O)(NCCCO1)N(CCCl)CCCl.O

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

description

Merck USA index - 14, 747

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 30 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

General description

A widely used anti-neoplastic agent that also displays immunosuppressant properties. Induces apoptotic cell death in rat thymus through the Fas/Fas ligand pathway.
A widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway.

Disclaimer

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fas/Fas ligand pathway
Product does not compete with ATP.
Reversible: no

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Wang, G.J., and Cai, L. 1999. Mutat. Res.427, 125.
Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.

Preparation Note

Solutions should be prepared fresh on the day of use.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

Certificates of Analysis (COA)

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