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250225

Cytochalasin B, Dihydro-

Induces changes in cell morphology and motility with no effect on sugar transport.

Synonym(s):

Cytochalasin B, Dihydro-

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About This Item

Empirical Formula (Hill Notation):
C29H39NO5
CAS Number:
39156-67-7
Molecular Weight:
481.62
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD12910542
Assay:
≥98% (TLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light
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Quality Level

100

description

Merck USA index - 14, 2790

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

methanol: 10 mg/mL, ethanol: 2 mg/mL, DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

N1[C@H]([C@H]3[C@@]4(OC(=O)CC[C@@H](CCC[C@H](C\C=C\[C@H]4[C@@H](C(=C)[C@H]3C)O)C)O)C1=O)Cc2ccccc2

InChI

1S/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1

InChI key

WIULKAASLBZREV-RXPQEOCGSA-N

General description

Induces changes in cell morphology and motility with no effect on sugar transport. Used as a specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Disrupts the equilibrium between monomeric and polymeric actin.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Changes in cell morphology and motility
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Lin, D.C., and Lin, S. 1978. J. Biol. Chem.253, 1415.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

signalword

Danger

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
250225-1MG04055977199130