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About This Item

Empirical Formula (Hill Notation):
C24H18N2O7
CAS Number:
Molecular Weight:
446.41
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.25
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Quality Level

Assay

≥98% (HPLC)

form

solution

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

pale yellow

fluorescence

λex ~495 nm
λem ~515 nm

storage temp.

−20°C

SMILES string

Nc1cc2c(cc1N)C(=O)OC32c4c(cc(cc4)OC(=O)C)Oc5c3ccc(c5)OC(=O)C

InChI

1S/C24H18N2O7/c1-11(27)30-13-3-5-16-21(7-13)32-22-8-14(31-12(2)28)4-6-17(22)24(16)18-10-20(26)19(25)9-15(18)23(29)33-24/h3-10H,25-26H2,1-2H3

InChI key

PTSUYDXEEKDBQU-UHFFFAOYSA-N

General description

A cell-permeable derivative of DAF-2 (Cat. No. 251500) that is hydrolyzed to DAF-2 by intracellular esterases. Can be used in fluorescence microscopy to measure real-time changes in NO levels in vivo.

Biochem/physiol Actions

Primary Target
Used to measure real-time changes in NO levels

Physical form

A 5 mM (1 mg/450 µl) solution in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Berkels, R., et al. 2000. Cell Calcium27, 281.
Kojima, H., et al. 1998. Anal. Chem. 70, 2446.
Kojima, H., et al. 1998. Chem. Pharm. Bull. 46, 373.
Nakatsubo, N., et al. 1998. FEBS Lett. 427, 263.

Legal Information

Manufactured by Daiichi Pure Chemicals Co., Ltd
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

188.6 °F - closed cup - (Dimethylsulfoxide)

Flash Point(C)

87 °C - closed cup - (Dimethylsulfoxide)


Certificates of Analysis (COA)

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