341326
Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem
Synonym(s):
7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor
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assay
≥98% (HPLC)
form
solid
color
white
solubility
DMSO: 50 mg/mL, clear, colorless
General description
A hydroxyquinolinone derivative that acts as a potent reversible inhibitor of type 1 fatty acid synthase (FAS) (IC50 = 19 nM) when enzyme activity is monitored by following the synthesis of free coenzyme A (CoA-SH).
The Fatty Acid Synthase Inhibitor, Cpd 10v, controls the biological activity of Fatty. This small molecule/inhibitor is primarily used for Cancer applications.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Certificates of Analysis (COA)
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