341492
FeTPPS
A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro.
Synonym(s):
FeTPPS, 5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride
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About This Item
Empirical Formula (Hill Notation):
C44H28ClFeN4O12S4
Molecular Weight:
1024.27
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (TLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
Quality Segment
assay
≥95% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
dark brown
solubility
water: soluble
shipped in
ambient
storage temp.
2-8°C
General description
A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
Biochem/physiol Actions
Cell permeable: no
EC50 = 5 µM for cytoprotection against peroxynitrite
Primary Target
Selective peroxynitrite scavenger
Selective peroxynitrite scavenger
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
Other Notes
Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci.914, 157.
Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.
Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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