36-012
Anti-nitro-α/β-Synuclein (Tyr39) Antibody, clone nSyn14
clone nSyn14, Upstate®, from mouse
Synonym(s):
Anti-NACP, Anti-PARK4, Anti-PD1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
nSyn14, monoclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
21
biological source
mouse
Quality Level
antibody form
ascites fluid
antibody product type
primary antibodies
clone
nSyn14, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
shipped in
dry ice
target post-translational modification
nitration (Tyr39)
Gene Information
human ... SNCA(6622)
General description
α-Synuclein, Mr 14.5kDa
β-Synuclein, Mr 17kDa
β-Synuclein, Mr 17kDa
Immunogen
full-length recombinant human α-Synuclein nitrated in vitro
Application
Anti-nitro-α/β-Synuclein (Tyr39) Antibody, clone nSyn14 detects level of nitro-α/β-Synuclein (Tyr39) & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Biochem/physiol Actions
α- or β-synuclein nitrated at Tyr39
Physical form
Ascites
Format: Purified
ascites with 0.05% sodium azide
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on recombinant protein nitrated in vitro
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
Certificates of Analysis (COA)
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Hugo Vicente Miranda et al.
Scientific reports, 7(1), 13713-13713 (2017-10-24)
Parkinson's disease (PD) is a progressive neurodegenerative disorder known for the typical motor features associated. Pathologically, it is characterized by the intracellular accumulation of alpha-synuclein (aSyn) in Lewy bodies and Lewy neurites. Currently, there are no established biochemical markers for
Pedro Magalhães et al.
NPJ Parkinson's disease, 8(1), 93-93 (2022-07-23)
Parkinson's disease (PD), the second most common progressive neurodegenerative disease, develops and progresses for 10-15 years before the clinical diagnostic symptoms of the disease are manifested. Furthermore, several aspects of PD pathology overlap with other neurodegenerative diseases (NDDs) linked to
Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
Duda, J. E., et al
Annals of Neurology, 52, 205-210 (2002)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 36-012 | 04053252331893 |