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About This Item
Empirical Formula (Hill Notation):
C10H11N5O7P · Na
CAS Number:
Molecular Weight:
367.19
UNSPSC Code:
41106305
NACRES:
NA.77
MDL number:
Assay:
>98% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic)
Quality Segment
description
Merck USA index - 14, 2709
assay
>98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
[Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2O)[n]3c4nc(nc(c4nc3)[O-])N)CO1)O
InChI
1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1
InChI key
KMPIYXNEROUNOG-GWTDSMLYSA-M
General description
An important intracellular second messenger implicated in mediating the action of nitric oxide in many cell types. Found to activate protein kinase G. Suppresses apoptosis in rat ovarian follicles.
Important intracellular second messenger implicated in the action of nitric oxide in many cell types. Activates protein kinase G. Suppresses apoptosis in rat ovarian follicles.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Activates protein kinase G
Activates protein kinase G
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Other Notes
Chun, S.Y., et al. 1995. Endocrinology136, 3120.
Kaupp, U.B., and Koch, K.W. 1992. Annu. Rev. Physiol.54, 153.
Goldberg, N.D., and Haddox, M.K. 1977. Annu. Rev. Biochem. 46, 823.
Kaupp, U.B., and Koch, K.W. 1992. Annu. Rev. Physiol.54, 153.
Goldberg, N.D., and Haddox, M.K. 1977. Annu. Rev. Biochem. 46, 823.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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