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370660

Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt

Name: Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt
Brand: MM

Cell-permeable cGMP analog that preferentially activates protein kinase G.

Synonym(s):

Guanosine 3′,5′-cyclic Monophosphate, N²,2′-O-Dibutyryl-, Sodium Salt, Dibutyryl-cGMP, Na

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₃N₅O₉P · Na

CAS Number:

51116-00-8

Molecular Weight:

507.37

MDL number:

MFCD00038422

UNSPSC Code:

41106305

NACRES:

NA.77

Assay:

≥95% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, desiccated (hygroscopic)

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Properties

Quality Level

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

ethanol: soluble, water: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2OC(=O)CCC)[n]3c4nc(nc(c4nc3)O)NC(=O)CCC)CO1)[O-]

InChI

1S/C18H24N5O9P.Na/c1-3-5-10(24)20-18-21-15-12(16(26)22-18)19-8-23(15)17-14(31-11(25)6-4-2)13-9(30-17)7-29-33(27,28)32-13;/h8-9,13-14,17H,3-7H2,1-2H3,(H,27,28)(H2,20,21,22,24,26);/q;+1/p-1/t9-,13-,14-,17-;/m1./s1

InChI key

MGBPJXVWDGGLKI-GBIKJYCISA-M

Description

General description

Cell-permeable cGMP analog that preferentially activates protein kinase G. Inhibits thrombin stimulated arachidonic acid release in human platelets.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Cell-permeable cGMP analog that preferentially activates protein kinase G.

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Sane, D.C., et al. 1989. Biochem. Biophys. Res. Commun.165, 708.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c