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About This Item

Empirical Formula (Hill Notation):
C3H3BrO3
CAS Number:
Molecular Weight:
166.96
MDL number:
UNSPSC Code:
12352200
EC Index Number:
214-206-5
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description

RTECS - UZ0840000

Quality Level

Assay

≥97% (titration)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

DMSO: 100 mg/mL
distilled water: 100 mg/mL

storage temp.

2-8°C

SMILES string

BrCC(=O)C(=O)O

InChI

1S/C3H3BrO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)

InChI key

PRRZDZJYSJLDBS-UHFFFAOYSA-N

General description

A cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Bujis, M., et al. 2009. Invest. New Drugs27, 120.
Chen, Z., et al. 2009. Biochim. Biophys. Acta.1787, 553.
Hulleman, E., et al. 2009. Blood.113, 2014;
Mathupala, S.P., et al. 2009. Semin. Cancer Biol.19, 17.
Pereira da Silva, A.P., et al. 2009. Biochem. J.417, 717.
Yun, J., et al. 2009. Science.325, 1555.
Zhang, X., et al. 2009. Anticancer Res.29, 1443.
Kim, J.S., et al. 2008. J. Bioenerg. Biomembr.40, 607.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Corrosive (L)

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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