400120
Human IgG1, Myeloma
Synonym(s):
Myeloma IgG₁
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Clone:
-
Species reactivity:
-
Application:
—
Citations:
5
assay
>95% (SDS-PAGE)
Quality Level
form
liquid
contains
≤0.1% sodium azide as preservative
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
−20°C
General description
Native IgG1 from human myeloma plasma. Purified from plasma of patients with myelomas producing IgG1 with kappa light chains.
Physical form
In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
Preparation Note
Prepared from plasma that was shown by certified tests to be negative for HBsAg and for antibodies to HCV, HBc, HIV-1 and HIV-2.
Other Notes
Single arc by immunoelectrophoresis against antiserum to whole human sera and human κ free and bound light chain. Note: the heavy chain of myeloma IgGs may appear as either a single or double band on gel electrophoresis. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
高风险级别生物产品--人源产品
This item has
Certificates of Analysis (COA)
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Anna Moroz et al.
Bioconjugate chemistry, 29(10), 3476-3482 (2018-09-20)
The swell of experimental imaging technologies to noninvasively measure immune checkpoint protein expression presents the opportunity for rigorous comparative studies toward identifying a gold standard. 89Zr-atezolizumab is currently in man, and early data show tumor targeting but also abundant uptake
Liliane Khoryati et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(9), 2221-2231 (2016-03-19)
Plasmacytoid dendritic cells (PDCs) play a central role in pathogenesis of systemic lupus erythematosus (SLE) through their unique ability to produce large amounts of type I interferon (IFN) upon Toll-like receptor 7 (TLR-7) and TLR-9 triggering. PDCs express specific surface
R B Cejas et al.
Scientific reports, 11(1), 10981-10981 (2021-05-28)
Persons with Down syndrome (DS, trisomy 21) have widespread cellular protein trafficking defects. There is a paucity of data describing the intracellular transport of IgG in the context of endosomal-lysosomal alterations linked to trisomy 21. In this study, we analyzed
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 400120-2MG | 04055977189308 |