407135-M
Caged Ins(1,4,5)P3, Trisodium Salt
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active and is not metabolized by endogenous phosphatase.
Synonym(s):
Caged Ins(1,4,5)P3, Trisodium Salt, D- myo-Inositol 1,4,5-Trisphosphate, P 4(5)-1-(2-Nitrophenyl)ethyl Ester, 3Na
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About This Item
Empirical Formula (Hill Notation):
C14H19NO17P3 · 3Na
Molecular Weight:
635.19
UNSPSC Code:
12352211
NACRES:
NA.77
Assay:
≥90% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, desiccated, protect from light
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
color
off-white
solubility
water: 1 mg/mL
storage temp.
−20°C
Quality Level
General description
Extinction coefficient (265 nm, H2O): 4240 M-1cm-1.
Note: 1 set = 10 x 10 µg.
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active and is not metabolized by endogenous phosphatase (extinction coefficient: 4240 M-1cm-1; 265 nm, H2O). A mixture of two isomers with a cage on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P3.
Biochem/physiol Actions
Primary Target
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Other Notes
Walker, J.W., et al. 1987. Nature327, 249.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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